Publications
What we have published
Selected work first, then everything else. Newest at the top of each list.
7 papers
Selected publications
Emerging roles and regulatory mechanisms involved in glutamine metabolism
Ryu, K.W., Fung, T.S., and Thompson, C.B.
Trends Biochem Sci · July 2026
Cellular ATP demand creates metabolically distinct subpopulations of mitochondria
Ryu, K.W., Fung, T.S., Baker, D.C., Saoi, M., Park, J., Febres-Aldana, C.A., Aly, R.G., Cui, R., Sharma, A., Fu, Y., et al.
Nature
Development and characterization of new tools for detecting poly(ADP-ribose) in vitro and in vivo
Challa, S.*, Ryu, K.W.*, Whitaker, A.L., Abshier, J.C., Camacho, C.V., and Kraus, W.L.
eLife 11
Metabolic regulation of transcription through compartmentalized NAD+ biosynthesis
Ryu, K.W., Nandu, T., Kim, J., DeBerardinis, R.J., and Kraus, W.L.
Science 360, 6389
PARP-1 controls the adipogenic transcriptional program by PARylating C/EBPβ and modulating its transcriptional activity
Luo, X.*, Ryu, K.W.*, Kim, D.S., Nandu, T., Medina, C.J., Gupte, R., Gibson, B.A., Soccio, R.E., Yu, Y., Gupta, R.K., and Kraus, W.L.
Mol Cell 65, 260–271
Who put the "A" in ATP? Generation of ATP from ADP-ribose in the nucleus for hormone-dependent gene regulation
Ryu, K.W., and Kraus, W.L.
Mol Cell 63, 349–351
New facets in the regulation of gene expression by ADP-ribosylation and poly(ADP-ribose) polymerases
Ryu, K.W.*, Kim, D.S.*, and Kraus, W.L.
Chem Rev 115, 2453–2481
9 papers
Other publications
Engineering mtDNA deletions by reconstituting end joining in human mitochondria
Fu, Y., Land, M., Kavlashvili, T., Cui, R., Kim, M., DeBitetto, E., Lieber, T., Ryu, K.W., Choi, E., Masilionis, I., et al.
Cell
Arginine: at the crossroads of nitrogen metabolism
Fung, T.S., Ryu, K.W., and Thompson, C.B.
The EMBO Journal 1–19
Lactate activates the mitochondrial electron transport chain independently of its metabolism
Cai, X., Ng, C.P., Jones, O., Fung, T.S., Ryu, K.W., Li, D., and Thompson, C.B.
Mol Cell 83, 3904–3920.e7
Ribosome ADP-ribosylation inhibits translation and maintains proteostasis in cancers
Challa, S., Khulpateea, B.R., Nandu, T., Camacho, C.V., Ryu, K.W., Chen, H., Peng, Y., Lea, J.S., and Kraus, W.L.
Cell
Mitochondrial NADP(H) generation is essential for proline biosynthesis
Zhu, J., Schwörer, S., Berisa, M., Kyung, Y.J., Ryu, K.W., Yi, J., Jiang, X., Cross, J.R., and Thompson, C.B.
Science 372, 968–972
Functional interplay between histone H2B ADP-ribosylation and phosphorylation controls adipogenesis
Huang, D., Camacho, C.V., Setlem, R., Ryu, K.W., Parameswaran, B., Gupta, R.K., and Kraus, W.L.
Mol Cell 79, 934–949.e14
Circadian oscillation of sulfiredoxin in the mitochondria
Kil, I.S., Ryu, K.W., Lee, S.K., Kim, J.Y., Chu, S.Y., Kim, J.H., Park, S., and Rhee, S.G.
Mol Cell 59, 651–663
Feedback control of adrenal steroidogenesis via H2O2-dependent, reversible inactivation of peroxiredoxin III in mitochondria
Kil, I.S., Lee, S.K., Ryu, K.W., Woo, H.A., Hu, M.C., Bae, S.H., and Rhee, S.G.
Mol Cell 46, 584–594
Regulation of poly(ADP-ribose) polymerase-1-dependent gene expression through promoter-directed recruitment of a nuclear NAD+ synthase
Zhang, T., Berrocal, J.G., Yao, J., DuMond, M.E., Krishnakumar, R., Ruhl, D.D., Ryu, K.W., Gamble, M.J., and Kraus, W.L.
J Biol Chem 287, 12405–12416
* co-first authorship · † corresponding authorship